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The Brain Ripples Before We Remember

Credit: Thinkstock Throw a stone into a quiet pond, and you’ll see ripples expand across the water from the point where it went in. Now, neuroscientists have discovered that a different sort of...

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New Study Points to Targetable Protective Factor in Alzheimer’s Disease

Credit: gettyimages/Creatista If you’ve spent time with individuals affected with Alzheimer’s disease (AD), you might have noticed that some people lose their memory and other cognitive skills more...

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New Grants Explore Benefits of Music on Health

It’s not every day you get to perform with one of the finest voices on the planet. What an honor it was to join renowned opera singer Renée Fleming back in May for a rendition of “How Can I Keep from...

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What a Memory Looks Like

Credit: Stephanie Grella, Ramirez Group, Boston University Your brain has the capacity to store a lifetime of memories, covering everything from the name of your first pet to your latest computer...

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A Real-Time Look at Value-Based Decision Making

All of us make many decisions every day. For most things, such as which jacket to wear or where to grab a cup of coffee, there’s usually no right answer, so we often decide using values rooted in our...

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Discovering the Brain’s Nightly “Rinse Cycle”

Getting plenty of deep, restful sleep is essential for our physical and mental health. Now comes word of yet another way that sleep is good for us: it triggers rhythmic waves of blood and...

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How Our Brains Replay Memories

Caption: Encoding and replaying learned memory. Left panel shows the timed sequence of neurons firing in a part of a person’s brain involved in memory as it encodes the random pair of words, “crow”...

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The People’s Picks for Best Posts

It’s 2021—Happy New Year! Time sure flies in the blogosphere. It seems like just yesterday that I started the NIH Director’s Blog to highlight recent advances in biology and medicine, many supported...

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The Synchronicity of Memory

Credit: Zhou Y, et al. FASEB J, 2020 You may think that you’re looking at a telescopic heat-map of a distant planet, with clickable thumbnail images to the right featuring its unique topography. In...

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Human Brain Compresses Working Memories into Low-Res ‘Summaries’

Credit: Adapted from Kwak Y., Neuron (2022) You have probably done it already a few times today. Paused to remember a password, a shopping list, a phone number, or maybe the score to last night’s...

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The Amazing Brain: Seeing Two Memories at Once

Credit: Stephanie Grella, Boston University, MA The NIH’s Brain Research Through Advancing Innovative Neurotechnologies® (BRAIN) Initiative is revolutionizing our understanding of the human brain. As...

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An Inflammatory View of Early Alzheimer’s Disease

Credit: Sakar Budhathoki, Mala Ananth, Lorna Role, David Talmage, National Institute of Neurological Diseases and Stroke, NIH Detecting the earliest signs of Alzheimer’s disease (AD) in middle-aged...

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